Hashimoto’s and Low Dose Naltrexone: An Alternative Treatment Option

Hashimoto’s and Low Dose Naltrexone: An Alternative Treatment Option is a video by Martin Rutherford that addresses the concerns and questions surrounding the use of Low Dose Naltrexone (LDN) for Hashimoto’s disease. As a chiropractor specializing in functional medicine and neurology, Dr. Rutherford shares his insights on LDN as a tool used by alternative doctors for autoimmune thyroid disease. He explains how LDN works to increase endorphins in the body, which can help to dampen inflammatory responses and provide relief for some patients. However, he emphasizes that LDN is not a cure-all solution and should be approached alongside other lifestyle changes, such as dietary modifications and addressing gut health. Dr. Rutherford acknowledges that LDN may not be suitable for everyone due to potential side effects like vivid dreams, but believes it is worth considering as an adjunctive therapy for those seeking additional support in managing the symptoms of Hashimoto’s disease.

In conclusion, Dr. Rutherford’s video provides a comprehensive overview of LDN as a treatment option for Hashimoto’s disease. He shares his experience in treating numerous Hashimoto’s patients and highlights the importance of combining LDN with other lifestyle changes and approaches to effectively manage the condition. It is important to note that the information provided in this video is for educational purposes only and should not substitute professional medical advice.


In the world of alternative medicine, Low Dose Naltrexone (LDN) has gained attention as a potential treatment option for Hashimoto’s, an autoimmune thyroid disease. While it is important to note that LDN is a medical procedure and should be approached with caution, many patients have reported positive results. In this comprehensive article, we will explore the basics of Hashimoto’s, the medical model for its treatment, the limitations of that model, and how LDN works in the body. We will also discuss the specific role of LDN in autoimmune thyroid disease and the potential benefits for Hashimoto’s patients. However, it is essential to consider certain factors before trying LDN and to consult with a qualified healthcare professional for personalized advice.

What is Hashimoto’s?

Hashimoto’s is an autoimmune thyroid disease that occurs when the immune system mistakenly attacks the thyroid gland. This leads to inflammation, which can cause a range of symptoms such as fatigue, weight gain, hair loss, depression, and joint pain. The exact cause of Hashimoto’s is not fully understood, but it is believed to be influenced by a combination of genetic and environmental factors.

Hashimotos and Low Dose Naltrexone: An Alternative Treatment Option

The Medical Model for Hashimoto’s Treatment

In the medical model for Hashimoto’s treatment, the focus is primarily on managing symptoms. Doctors may prescribe thyroid hormone replacement therapy to help regulate hormone levels and alleviate symptoms. However, this approach does not address the underlying autoimmune response causing the condition. Instead, it aims to balance hormone levels by providing artificial hormones.

The Limitations of the Medical Model

One of the main limitations of the medical model for Hashimoto’s treatment is its narrow focus on hormone replacement therapy. While this can be effective in reducing symptoms, it does not address the root cause of the autoimmune response. Additionally, some patients may experience adverse reactions to specific formulations or have difficulties finding the right dosage. Furthermore, the medical model does not typically incorporate a comprehensive approach to autoimmune conditions, such as uncovering and addressing triggers or promoting overall immune system health.

Hashimotos and Low Dose Naltrexone: An Alternative Treatment Option

What is Low Dose Naltrexone (LDN)?

Low Dose Naltrexone (LDN) is a medication that was originally developed to treat alcohol and opioid addiction at higher doses. However, it has gained attention in the alternative medicine community for its potential effects on autoimmune conditions. LDN works by modulating the body’s immune response and increasing the production of endorphins.

How LDN Works in the Body

LDN works by inhibiting certain receptors in the brain, which leads to an increase in endorphins. Endorphins are natural chemicals that act as pain relievers and mood enhancers. In addition to their effects on pain and mood, endorphins can also modulate the immune system. By increasing the production of endorphins, LDN may help regulate the immune response and reduce inflammation in autoimmune conditions like Hashimoto’s.

Hashimotos and Low Dose Naltrexone: An Alternative Treatment Option

The Role of LDN in Autoimmune Thyroid Disease

In the context of autoimmune thyroid disease, LDN’s role is to modulate the immune response, thereby reducing inflammation and potentially slowing the progression of the disease. By dampening the inflammatory response, LDN may help alleviate symptoms associated with Hashimoto’s, such as fatigue and joint pain. However, it is important to note that LDN is not a cure for Hashimoto’s, but rather a tool that can assist in managing the condition.

The Benefits of LDN for Hashimoto’s Patients

There are several potential benefits of LDN for Hashimoto’s patients. Some individuals have reported improvements in energy levels, mood, and overall well-being while using LDN. Additionally, LDN may help decrease thyroid antibody levels, which are often elevated in Hashimoto’s. By reducing inflammation in the thyroid gland, LDN may also support thyroid function and reduce the need for high doses of synthetic hormones.

Considerations Before Trying LDN

Before considering LDN as a treatment option for Hashimoto’s, there are several important factors to take into account. First and foremost, it is crucial to consult with a qualified healthcare professional who can assess your individual case and provide personalized advice. LDN is a prescription medication, and it should only be taken under medical supervision. Additionally, it is essential to address any underlying triggers or contributing factors to Hashimoto’s, such as dietary changes, gut health, and lifestyle adjustments. LDN should not be seen as a standalone solution but rather as one part of a comprehensive treatment plan.


While Low Dose Naltrexone (LDN) may hold promise as a treatment option for Hashimoto’s and other autoimmune conditions, it is important to approach it with caution and under the guidance of a qualified healthcare professional. LDN works by modulating the immune response and reducing inflammation, potentially alleviating symptoms and supporting thyroid function in Hashimoto’s patients. However, it is not a cure, and its effectiveness may vary from person to person. By considering LDN within a comprehensive treatment plan and addressing underlying triggers, individuals with Hashimoto’s may find additional support in managing their condition. Always remember to consult with a healthcare professional for personalized advice and guidance.